How Do You Spell CALCITRIOL RECEPTOR?

1. Calcitriol receptor, also known as the vitamin D receptor (VDR), is a specific cellular protein that belongs to the superfamily of nuclear receptors. It functions as a transcription factor, meaning it regulates the expression of genes involved in various biological processes. The calcitriol receptor has a high affinity for the active form of vitamin D called calcitriol or 1,25-dihydroxyvitamin D3.

   When calcitriol enters a cell, it binds to the calcitriol receptor, forming a complex that can then bind to specific DNA sequences called vitamin D response elements (VDREs). This binding of the receptor to VDREs influences the transcription of target genes, either promoting or inhibiting their expression depending on the specific gene and cellular context.

   The main role of the calcitriol receptor is to mediate the effects of vitamin D on calcium and phosphate metabolism. Activation of the receptor by calcitriol leads to the increase in intestinal absorption of calcium, reabsorption of calcium in the kidneys, and the release of calcium from bones. It also promotes the absorption of phosphate from the intestines and helps maintain normal levels of these minerals in the body.

   Aside from its role in calcium homeostasis, the calcitriol receptor is also involved in cell differentiation, proliferation, and immune function. It regulates the expression of genes related to cellular growth, differentiation, and apoptosis, as well as genes associated with immune response and inflammation.

   Overall, the calcitriol receptor is a critical component in the biological actions of vitamin D, playing a pivotal role in multiple physiological processes.

Common Misspellings for CALCITRIOL RECEPTOR

The word "Calcitriol Receptor" consists of two parts: "Calcitriol" and "Receptor.

1. Calcitriol: The term "calcitriol" is derived from the combination of "calcium" and "triole", with "calc" representing calcium and "triole" indicating a form of vitamin D. Calcitriol is the active form of vitamin D, which is responsible for regulating calcium and phosphate levels in the body.

2. Receptor: The term "receptor" comes from the Latin word "receptus", which means "to receive". In biology, a receptor is a protein molecule found on the surface or within a cell that binds to a specific substance, such as a hormone or neurotransmitter, to initiate a physiological response.