GFAP Meaning and
Definition
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GFAP stands for Glial Fibrillary Acidic Protein. It is a type III intermediate filament protein that is primarily found in astrocytes, which are star-shaped glial cells in the central nervous system (CNS).
GFAP is an important marker for astrocytes and is often used as a specific marker to identify and study these cells. It helps maintain the structural integrity of astrocytes and plays a crucial role in their function.
The protein is encoded by the GFAP gene and is primarily expressed in mature astrocytes, although it can also be found in some other cell types under certain conditions, such as during development or in response to injury or disease.
GFAP is involved in various cellular processes, including cell motility, migration, and maintaining the shape of astrocytes. It also serves as a scaffold for other proteins and is involved in signaling pathways. Changes in GFAP expression or structure have been associated with various neurological disorders and brain injuries, such as Alzheimer's disease, multiple sclerosis, and traumatic brain injury.
In summary, GFAP is a protein found primarily in astrocytes in the CNS. It plays a key role in maintaining astrocyte structure and function and is involved in various cellular processes. Its expression and structure can be altered in various neurological disorders and brain injuries.
Common Misspellings for GFAP
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