GSDIII Meaning and
Definition
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GSDIII, or Glycogen Storage Disease Type III, is a genetic disorder characterized by the inability of the body to properly break down glycogen, a form of stored glucose or sugar. Glycogen is typically broken down into glucose molecules as needed to provide energy for the body's cells. However, individuals with GSDIII lack an enzyme called glycogen debranching enzyme, which is responsible for breaking down glycogen molecules into glucose.
As a result, individuals with GSDIII experience an accumulation of abnormal glycogen in various tissues, especially the liver and muscles. This glycogen buildup disrupts normal cellular functions and can lead to a wide range of symptoms. These may include low blood sugar levels, fatigue, muscle weakness, enlarged liver, and growth retardation in children.
The severity and specific symptoms of GSDIII can vary widely from person to person. Some individuals may have relatively mild symptoms and can lead relatively normal lives with careful dietary management. Others may develop more severe complications such as liver cirrhosis, heart problems, or muscle wasting. Treatment for GSDIII typically involves managing symptoms through diet and regular medical monitoring, including careful regulation of carbohydrate intake and continuous monitoring of blood sugar levels.
GSDIII is inherited in an autosomal recessive manner, meaning that both parents must carry a mutated copy of the gene responsible for the disorder for their child to inherit it. Genetic counseling and prenatal testing are often recommended for families with a history of GSDIII to assess the risk of passing the disorder to future generations.
Common Misspellings for GSDIII
- fsdiii
- vsdiii
- hsdiii
- ysdiii
- tsdiii
- gadiii
- gzdiii
- gxdiii
- gddiii
- gwdiii
- gssiii
- gsxiii
- gsfiii
- gsriii
- gseiii
- gsduii
- gsdjii
- gsdkii
- gsdoii
- gsd9ii
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