How Do You Spell MYXODERMIA?

1. Myxodermia is a medical term that refers to a rare condition characterized by localized or diffuse swelling and thickening of the skin due to the abnormal accumulation of mucopolysaccharides in the connective tissues. Also known as pretibial myxedema, this condition primarily affects the lower legs, particularly the shin area, although it can sometimes appear on other parts of the body as well.

   The underlying cause of myxodermia is often associated with autoimmune thyroid disorders, particularly Graves' disease. It is believed that in some individuals with Graves' disease, the immune system produces antibodies that mistakenly target the tissues in the lower legs, leading to the overproduction of proteins called glycosaminoglycans. This excessive accumulation of these substances in the connective tissues causes edema, or fluid retention, leading to the characteristic swelling and thickening of the skin.

   The symptoms of myxodermia may include pain, redness, pruritus (itching), and a lumpy or nodular texture of the affected skin. In severe cases, it can lead to mobility issues and limit the range of motion in the affected limb.

   Treatment for myxodermia typically involves managing the underlying autoimmune thyroid disorder, often through medications such as antithyroid drugs or radioactive iodine therapy. Additionally, topical corticosteroids or compression garments may be used to alleviate symptoms and reduce swelling.

   In conclusion, myxodermia is a rare medical condition characterized by localized or diffuse swelling and thickening of the skin, primarily affecting the lower legs. It is often associated with autoimmune thyroid disorders, and treatment focuses on managing the underlying condition while providing symptom relief.

2. Edematous softening of the skin.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for MYXODERMIA

The word "myxodermia" is derived from two Greek roots: "myxo" and "derma".

The term "myxo" (μυξο) means "mucus" or "slime" in Greek. It is often used to refer to a slimy or gelatinous substance.

The root "derma" (δέρμα) means "skin" in Greek. It is commonly used in medical terminology to indicate something related to the skin.

Therefore, when combined, "myxodermia" refers to a condition or disease that affects the skin and is characterized by an abnormal accumulation of mucus or a gelatinous substance.