How Do You Spell WHITE SUBSTANCE OF SCHWANN?

1. The white substance of Schwann, also known as myelin, is a specialized white, fatty material that surrounds and insulates nerve fibers in the peripheral nervous system. It is named after the Swiss anatomist Theodor Schwann who described this substance in the 19th century. Myelin serves as an important protective layer, facilitating the efficient transmission of electrical impulses along the nerve fibers.

   The white substance of Schwann is composed of multiple layers of myelin, which are formed by the plasma membrane of cells called Schwann cells. These cells wrap around the nerve fibers, creating a segmented appearance with gaps or nodes of Ranvier in between each segment. The myelin acts as an insulator, preventing electrical signals from diffusing out of the nerve fibers and enhancing their conduction speed.

   By virtue of its white color, the white substance of Schwann contributes to the appearance of white matter in the central nervous system where myelinated nerve fibers predominantly reside. It plays a crucial role in facilitating rapid and efficient transmission of nerve impulses, enabling precise communication between different parts of the body.

   Disorders affecting the white substance of Schwann, such as demyelinating diseases like multiple sclerosis, can lead to impaired nerve signaling. Damage to the myelin sheath can result in reduced or interrupted transmission of nerve impulses, leading to various neurological symptoms and impairments. Understanding the structure and function of the white substance of Schwann is fundamental to comprehending the underlying mechanisms and potential treatments for these conditions.

2. See Schwann.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

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